
Men's Health
Male Hormones After 40: Changes You Shouldn't Ignore

By
Dre Roxanne Ouellet
Mar 2, 2025
Experiencing fatigue, weight gain, or mood changes as a man over 40? Learn how age-related hormonal shifts affect men's health and how bioidentical hormone therapy can help restore energy, focus, and vitality.
When conversations about hormones arise, they often center on women's health. However, at Clinique DRO, we recognize that men experience significant hormonal transitions too—often with symptoms that are mistakenly attributed to "just getting older" rather than recognized as treatable hormonal imbalances.
The Reality of Male Hormonal Changes
Unlike the relatively rapid hormonal shifts women experience during menopause, men typically undergo a gradual decline in testosterone and other key hormones—a process sometimes called "andropause." This decline usually begins around age 30, with noticeable symptoms often emerging in the 40s and beyond.
While this hormonal transition is natural, its effects can significantly impact quality of life, physical health, and emotional wellbeing. More importantly, these changes don't have to be passively accepted as inevitable aspects of aging.
Key Hormonal Shifts Men Experience
Testosterone Decline: Testosterone decreases by approximately 1-2% annually after age 30. By 40-50, many men have levels low enough to cause noticeable symptoms.
Estrogen Fluctuations: Contrary to popular belief, men need some estrogen for optimal health. However, as testosterone declines, the testosterone-to-estrogen ratio often becomes imbalanced.
Thyroid Changes: Thyroid function can decrease with age, affecting metabolism and energy levels.
Cortisol Imbalances: Chronic stress can disrupt cortisol patterns, further impacting testosterone production and overall hormonal balance.
Symptoms You Shouldn't Dismiss
If you're experiencing these changes, don't write them off as inevitable signs of aging:
Physical Changes:
Increased body fat, especially around the abdomen
Decreased muscle mass despite continued exercise
Reduced strength and stamina
Difficulty recovering from workouts
Hair loss beyond typical male pattern baldness
Mental and Emotional Shifts:
Brain fog or difficulty concentrating
Memory lapses
Mood swings or irritability
New or worsening anxiety
Low motivation or apathy
Depression symptoms
Sexual Health Changes:
Decreased libido
Erectile dysfunction
Reduced sexual satisfaction
Decreased morning erections
Sleep and Energy Issues:
Chronic fatigue despite adequate sleep
Difficulty falling or staying asleep
Increased need for caffeine or other stimulants
Afternoon energy crashes
How Bioidentical Hormone Therapy Can Help
At Clinique DRO, we specialize in helping men restore hormonal balance through personalized bioidentical hormone therapy. Unlike synthetic hormones, bioidentical hormones are molecularly identical to those your body produces naturally, typically resulting in fewer side effects and better symptom relief.
Real Results Our Male Patients Experience
Many of our male patients report significant improvements within weeks of beginning bioidentical hormone therapy:
Increased energy and motivation
Improved body composition (more muscle, less fat)
Enhanced mental clarity and focus
Better mood stability
Restored libido and sexual function
Improved sleep quality
Greater stress resilience
Taking the First Step
If you're experiencing symptoms of hormonal imbalance, the first step is a comprehensive evaluation. Many men hesitate to seek help, assuming their symptoms are just part of getting older or fearing they'll be dismissed by healthcare providers.
At Clinique DRO, we take men's hormonal health seriously. We understand the complex interplay of hormones in the male body and recognize that optimal hormonal function is essential for overall health, not just a luxury.
Don't accept diminished quality of life as an inevitable part of aging. Contact our clinic to schedule a consultation and discover how bioidentical hormone therapy might help you reclaim your energy, focus, strength, and vitality.
Start Your Journey Here
Contact us today and discover how we can help you feel like yourself again.